Ka hoʻohana ʻana o ke keleawe Hydroxy Methionine 1

Nā Hoʻohana Huahana

1) Nā ʻīlio hoʻomoʻa

I ka wā e hoʻohana ai nā MMHAC (nā chelates hydroxy methionine o ke keleawe, zinc, a me manganese) i nā meaʻai broiler, ua hōʻike nā hopena—i ka hoʻohālikelike ʻia me nā minelala trace inorganic kuʻuna—ʻo ka hoʻokomo ʻia ʻana o nā MMHACs i hoʻonui nui i ke kaumaha o ke kino a me ke kaumaha o nā ʻiʻo drumstick (ʻūhā), hoʻomaikaʻi i ka digestibility keleawe, a ʻaʻole i hoʻopilikia i ke olakino gizzard a i ʻole ka iwi.

Papa 1. Kaumaha hana kupapaʻu (g/manu) a me nā helu kaha keʻokeʻo o ka umauma lāʻau a me ka umauma o nā broilers i hānai ʻia me ka inorganic a me ka methionine hydroxyl analogue chelated zinc, keleawe, a me ka manganese dietary treatment Pōʻaono lā 42.

Mea	ITM	M10	T125	M30	SEM	Waiwai-P
ʻŪhā	684	716	719	713	14.86	0.415
ʻūhā	397	413	412	425	7.29	0.078
Pahu lāʻau	320	335	332	340	4.68	0.058
ʻUha a me ka drumstick	717 a	748 ab	745 ab	765 b	11.32	0.050
Papa momona	32.3	33.1	33.4	35.5	1.59	0.546
Ake	68.0	67.4	66.0	71.1	2.41	0.528
Puʻuwai	18.8	18.6	19.2	19.2	0.68	0.898
Pūpū	9.49	10.2	10.6	10.6	0.51	0.413

Nānā: ITM: Mineral trace inorganic 110 ppm Zn ma ke ʻano he ZnSO4 16 ppm Cu ma ke ʻano he CuSO4 a me 120 ppm Mn ma ke ʻano he MnO e like me nā ʻōlelo paipai meaʻai a Ross 308;

M10: Nā nui o 40 ppm Zn 10 ppm Cu a me 40 ppm Mn ma ke ʻano he chelate;

T125: Mineral trace inorganic 110 ppm Zn ma ke ʻano he ZnSO4 a me 120 ppm Mn ma ke ʻano he MnO e like me nā alakaʻi Ross 308 me 125 ppm Cu ma ke ʻano he tribasic copper chloride (TBCC);

ʻO M30 = 40 ppm Zn, 30 ppm Cu, a me 40 ppm Mn ma ke ʻano he chelate. ʻOkoʻa loa nā waiwai ma ka lālani like me nā superscripts like ʻole (P < 0.05).

2) Nā puaʻa

Ua noiʻi ʻia e kahi noiʻi nā hopena o ka hoʻololi hapa ʻana i nā minelala trace inorganic me ka mineral methionine hydroxy analogue chelates (MMHAC) i nā meaʻai puaʻa ma nā puaʻa a me kā lākou mau puaʻa. Ua hōʻike ʻia nā hopena ua hōʻemi ka hoʻohui ʻana o MMHAC i ka pohō kaumaha o ke kino i nā puaʻa hānai, hoʻolaha i ka piʻi ʻana o ke kaumaha o ke kino o ka puaʻa i ka lā 18, hoʻonui nui i nā pae histone acetylation o ka ʻiʻo skeletal i ka wā hānau, a hoʻohaʻahaʻa i ka hōʻike ʻana o nā genes he nui e pili ana i ka mumū a me ka ulu ʻana o nā ʻiʻo. Ma keʻano holoʻokoʻa, ua hoʻomaikaʻi ka MMHAC i ke olakino ʻōpū a me ka ulu ʻana o nā ʻiʻo i nā puaʻa ma o ka hoʻoponopono epigenetic a me ka hoʻomohala ʻana, e hoʻonui ana i ko lākou hiki ke ulu.

Papa 2 Nā hopena hoʻohui o ka mineral methionine hydroxy analogue chelate i nā meaʻai puaʻa ma ka hōʻike ʻana o ka mRNA koʻikoʻi e pili ana i ka mumū jejunal i ka puaʻa hānai

Mea	ITM	CTM	SEM	P- waiwai
d 1 o ka lactation x 10^-5
IL-8	1344	1018	178	0.193
MUC2	5380	5511	984	0.925
NF-κB (p50)	701	693	93	0.944
NF-κB (p105)	1991	1646	211	0.274
TGF-b1	Mai ka makahiki 1991	1600	370	0.500
TNF-α	11	7	2	0.174
d 18 o ka lactation x 10^-5
IL-8	1134	787	220	0.262
MUC2	5773	3871	722	0.077

Nānā: Interleukin-8 (IL-8), mucin-2 (MUC2), nuclear factor-κB (NF-κB), transforming growth factor-1 (TGF-1), a me ka tumor necrosis factor-α (TNF-α)

ITM = nā kumu inorganic maʻamau o nā minelala trace (0.2% pae hoʻokomo i loko o nā meaʻai)

CTM = 50:50 mineral methionine hydroxy analogue chelate a me nā minelala inorganic (0.2% pae hoʻokomo i loko o nā meaʻai)

3)Nā ʻīlio rumanina

I loko o nā bipi waiū hānai, e pani ana i ka hapalua o ke keleawe sulfate mekeleawe hydroxy methionineua hoʻonui nui ʻia ka nui o ke keleawe plasma, ua hoʻomaikaʻi i ka digestibility o ka fiber detergent neutral (NDF) a me ka fiber detergent acid (ADF), a ua hoʻonui i ka hua waiū a me ka hana waiū i hoʻoponopono ʻia i ka momona 4%. Hōʻike kēia mau ʻike he hoʻolālā meaʻai ʻoi aku ka maikaʻi o ka hoʻololi ʻana i ke keleawe sulfate me (HMTBA)₂-Cu i nā meaʻai bipi waiū.

Ka hoʻomomona ʻana i nā bipi a me nā hipa

Papa 3 Nā hopena o ka methionine hydroxy Cu [(HMTBA)2-Cu] ma ka hoʻohuihui waiū o nā bipi wahine

Mea	S	SM	M	SEM	Waiwai-P
DMI, kg/lā	19.2	20.3	19.8	0.35	0.23
Ka hua waiū, kg/d	28.8	33.8	31.3	1.06	0.08
Momona, %	3.81	3.74	3.75	0.06	0.81
Pūmua, %	3.34	3.28	3.28	0.04	0.19
Laktose, %	4.48	4.35	4.43	0.05	0.08
SNF, %	8.63	8.84	8.63	0.05	0.33
Ka hua momona, kg/d	1.04	1.22	1.10	0.04	0.09
Ka hua o ka protein, kg/d	0.92	0.92	0.90	0.03	0.72
Ka hua lactose, kg/d	1.23	1.23	1.21	0.04	0.45
ʻUrea N, mg/dL	18.39	17.70	18.83	0.45	0.19
4% FCM, kg/lā	26.1	30.1	27.5	0.91	0.06

Nā Lapaʻau: S = Cu sulfate wale nō: 12 mg o Cu i hāʻawi ʻia e CuSO4 no ke kilokani o ka mea hoʻohuihui; SM = Cu sulfate a me (HMTBA)2-Cu: 6 mg o Cu i hāʻawi ʻia e CuSO4, a me kekahi 6 mg o Cu i hāʻawi ʻia e (HMTBA)2-Cu no ke kilokani o ka mea hoʻohuihui; M = (HMTBA)2-Cu wale nō: 12 mg o Cu i hāʻawi ʻia e (HMTBA)2-Cu no ke kilokani o ka mea hoʻohuihui.